6S RNA Function Enhances Long-Term Cell Survival

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6S RNA function enhances long-term cell survival.

6S RNA was identified in Escherichia coli >30 years ago, but the physiological role of this RNA has remained elusive. Here, we demonstrate that 6S RNA-deficient cells are at a disadvantage for survival in stationary phase, a time when 6S RNA regulates transcription. Growth defects were most apparent as a decrease in the competitive fitness of cells lacking 6S RNA. To decipher the molecular mech...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2004

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.186.15.4978-4985.2004